Ujjwal Neogi, M.Sc., PhD
Division of Clinical Microbiology; F68
Department of Laboratory Medicine
141 86 Stockholm, Sweden
Phone: +46 (0) 8524 83680
Mobile: +46 (0) 7032 77013
The aim of my research group is through translational research integrating the multi-omics techniques and the clinical data to understand the disease control mechanism in a group of HIV-1 positive individuals, who control viral replication and restrained progression to AIDS, without any antiretroviral therapy for a longer duration of time (Elite controller). In a systemic approach, we apply the molecular data-first approach (using Genomics, transcriptomics, proteomics and metabolomics) classifies persistent genetic variants or expression patterns in order to reduce host influenced heterogeneity followed by the phenotypic profiling, virological and immunological characterizations of the disease control mechanism. This understanding of the unique gene expression and immunological characteristics of EC will predict a frame of reference for what may be required in clinical intervention strategies to induce immune control of HIV-1 and the future development of functional HIV-cure.